http://www.ozyandmillie.org/index2.html
I'm liking the idea of changing the layout, but I'm not keen on the new title, mainly because it has a tagline and I've always felt O&M doesn't need one. Also the positioning of the date and strip name looks a bit odd where it is as it doesn't line up with anything, maybe it would be better to have the strip name where the tagline is or back to where it used to be under the strip?
Also the news box and all the blank blue space looks untidy, but I think that's because of the sidebar rather then anything else.
As I said though, I think tis a good idea to change it so keep up the good work.